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【医学部学术讲座】——Functional Connectivity at High Temporal Resolution in fMRI

文章来源: 作者: 发布时间:2018年04月08日 点击数: 字体:

主讲嘉宾: Bharat Bhusan Biswal , Distinguished Professor

Department of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ, 07029, USA

School of Life Sciences and Technology, University of Electronic Science and Technology of China

 

时间:     2018年4月16日上午 10:00 – 11:00

地点:     深圳大学西丽校区A2-517

主持人:   张治国 教授

报告内容简介:

In recent years, there has been an increasing interest to study resting functional connectivity in both healthy subjects and clinical populations using fMRI. In most fMRI studies, it is implicitly assumed, that signal giving rise to temporal correlation across voxels (or regions) is dominated by low frequency fluctuations (in the range of 0.01 – 0.1 Hz). Advances in parallel excitation and reconstruction methodology have enabled researchers to acquire whole brain data at higher temporal resolution without any loss in spatial resolution. In this study, we test two specific hypotheses: 1. Does higher frequency (>0.1 Hz) contribute to significant temporal correlation; 2) Are the temporal and spectral properties between the different resting state networks significantly different.

报告嘉宾简介:

Biswal教授是国际顶级脑成像专家,是静息态脑功能磁共振成像(resting-state fMRI)的鼻祖,率先提出了静息态脑功能活动概念,建立了用fMRI研究大脑静息态连接和网络的方法,该方法现已在正常脑功能和脑疾病研究中得到广泛应用。Biswal教授还联合创建了“FCON_1000”数据库。该数据库是目前最大的fMRI公开数据集,已实现面向全球神经研究中心收集脑功能成像数据,为描绘和理解大脑功能提供了公开的研究资源;至今,此数据库已包含1400余位病人的神经信息数据且全球下载次数已超过5000次。自2012年起,Biswal就入选汤森路透发布的“全球高被引科学家”;2015年入选“World's Most Influential Scientific Minds”的科学家之一,其论文被引数名列“ISI高被引”神经学科与行为领域前100位。至今,他已在 PNAS, Cerebral Cortex, Journal of Neuroscience, Neuroimage, Human Brain Mapping 等国际知名期刊发表相关论文150多篇。Google引用约22000次,H指数55次,其中被引100次以上文章36篇、300次以上13篇、500次以上10篇、5000次以上1篇。

 

Prof. Biswal is the intellectual father of resting state, functional connectivity with fMRI and is personally responsible for a paradigm shift in imaging neuroscience. His contributions have been enormous; ranging from a deeper understanding of endogenous brain activity through to important strategic initiatives in neuro-informatics and data-sharing. His early work established resting state functional connectivity as a way of probing functional brain architectures (Biswal et al., MRM 34). This work underlies a substantial proportion of current fMRI studies in the literatures. Academically, Prof. Biswal’s impact is reflected in the fact that he is an ISI highly cited researcher in neuroscience and behavior and is the author of some of the most highly cited papers in clinical imaging (2014 – present). So far, he has authored and co-authored 150 articles appearing in peer-reviewed journals. His work has appeared in high-profile journals in psychology, neuroscience, and engineering, including Proceedings of the National Academy of Sciences, Cerebral Cortex, NeuroImage, Journal of Neuroscience, and Human Brain Mapping. His work has been cited around 22,000 times with a H-index of 55. Ten of his papers have been cited more than 500 times, with one paper receiving more than 5000 citations (google scholar).

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