Name：Zhourui Xu

Position：Assistant Professor

E-mail：xuzhouray@szu.edu.cn

Personal Statement:

Dr. Zhourui Xu obtained his Ph.D. from The Hong Kong Polytechnic University in 2020, followed by postdoctoral training at the School of Biomedical Engineering, Shenzhen University. He was promoted as Assistant Professor at the same institution in 2023 and recognized as a recipient of the Pengcheng Peacock Plan for Overseas High-Level Talents in Shenzhen. 

Fluorescence imaging and phototherapy have emerged as pivotal biomedical technologies, distinguished by their high spatiotemporal resolution, minimal invasiveness, operational simplicity, and proven therapeutic efficacy. Dr. Xu's research focuses on two fundamental requirements in photo-based bioapplications: 1) maximizing light energy utilization efficiency, and 2) optimizing light energy conversion efficiency. His work aims to develop innovative nanoparticle-based healthcare systems that bridge the gap between cutting-edge photonic technologies and clinical diagnostic/therapeutic requirements. As first/co-corresponding/corresponding author, Dr. Xu has published extensively in top-tier journals including Advanced Materials, ACS Nano, Applied Physics Reviews, Chemical Engineering Journal, and Materials Horizons. His research provides critical theoretical frameworks and technological breakthroughs for advancing the applications of phototheranostic systems in the biomedical field.

Research Interests:

Two/Three-Photon imaging

Phototheranostics

Implantable light sources

Research Projects:

1. National Natural Science Foundation of China Project (62205216):  01/01/2023 to 12/31/2025  ￥300,000

2. Guangdong Natural Science Foundation (2025A1515010016):  01/01/2025 to 12/31/2027 ￥100,000

3. Shenzhen Medical Research Fund (A2403014): 01/01/2025 to 12/31/2027 ￥800,000

4. Basic Research Foundation of Shenzhen (JCYJ20240813143321028): 11/01/2024 to 10/31/2027 ￥300,000

5. Shenzhen Peacock Start-up Grant:  01/01/2025 to 12/31/2027 ￥3,000,000

Selected Peer-reviewed Publications:

1. Zhourui Xu^#, Xue Li^#, Zengming Yang, Zhijun Zhang, Yibin Zhang, Miaozhuang Fan, Yuying Zeng, Miaomiao Kang*, Yuanyuan Shen*, Dong Wang*, Gaixia Xu, Ben Zhong Tang*, An NIR-II Two-Photon Excitable AIE Photosensitizer for Precise and Efficient Treatment of Orthotopic Small-Size Glioblastoma, Adv. Mater.2024, 202413164. (Nature Index)

2. Wenguang Zhang^#, Miaomiao Kang^#, Xue Li, Yinzhen Pan, Zhuorong Li, Yibin Zhang, Changrui Liao, Gaixia Xu, Zhijun Zhang*, Ben Zhong Tang*, Zhourui Xu*, Dong Wang*, Fiber Optic-Mediated Type I Photodynamic Therapy of Brain Glioblastoma Based on an Aggregation-Induced Emission Photosensitizer, Adv. Mater. 2024, e2410142. (Nature Index)

3. Wenguang Zhang^#, Miaomiao Kang^#, Xue Li, Hao Yang, Zhijun Zhang*, Zhuorong Li, Yibin Zhang, Miaozhuang Fan, Changrui Liao, Chengbo Liu, Gaixia Xu*, Dong Wang*, Zhourui Xu*, Ben Zhong Tang*, Interstitial Optical Fiber-Mediated Multimodal Phototheranostics Based on an Aggregation-Induced NIR-II Emission Luminogen for Orthotopic Breast Cancer Treatment, Adv. Mater. 2024, 2406474. (Nature Index)

4. Zhourui Xu^#, Zhijun Zhang^#, Xiangquan Deng, Jiangao Li, Yihang Jiang, Wing-Cheung Law, Chengbin Yang, Wanjian Zhang, Xiaolin Chen, Ke Wang*, Dong Wang*, Gaixia Xu*, Deep-Brain Three-Photon Imaging Enabled by Aggregation-Induced Emission Luminogens with Near-Infrared-III Excitation, ACS Nano 2022, 16(4), 6712–6724. (Nature Index)

5. Miaozhuang Fan^#, Zhourui Xu^#, Maixian Liu^#, Yihang Jiang, Xiaomin Zheng, Chengbin Yang, Wing-Cheung Law, Ming Ying, Xiaomei Wang, Yonghong Shao, Mark T Swihart, Gaixia Xu*, Ken-Tye Yong*, Ben Zhong Tang*, Recent advances of luminogens with aggregation-induced emission in multi-photon theranostics, Appl. Phys. Rev. 2021, 8(4), 041328.