NAME: Zhao Zhenfu

POSITION TITLE: Associated Professor of Anatomy & Histology; Director of the Teaching Office, Shenzhen University School of Medicine

EDUCATION/TRAINING

A.   Personal Statement

Prior to my current position at Shenzhen University, I spent 12 years teaching anatomy and conducting research in the field of clinical anatomy. In 2008, I joined the Shenzhen University, School of Medicine as an Associate Professor of Anatomy. Since 2011, I have served as the Director of the Teaching Office. I have spent a lot of time engaging with students and designing their work program, such as the medical training program and practicing the teaching method of PBL (problem based learning). I also perform research that focuses on nerve regeneration and diagnostic reagents development.

B.   Positions and Honors

Positions and Employment

0 9 /199 6 – 10/ 2008      Teacher, Department of Anatomy, Jiamusi University, Jiamusi, China

11 /20 08 – present       Associate Professor and Director of Teaching Office, Shenzhen University School of Medicine, Shenzhen, China

C.   Publications (*: corresponding/co- first author)

1. Zhao ZF, Gao GQ, Liu S, Zou JT, Xie Y, Yuan QF,Wang HQ and Yao ZB. Screening for a human single chain Fv antibody against epitope on amyloid-beta1-40 from a human phage display library. Chinese Medical Journal. 2007,120(21):1931-1934（IF：1.016）

2. Zhe Jin*, Zhenfu Zhao*, Yulan Cheng, Ming Dong, Xiaojing Zhang, Liang Wang, Xinmin Fan, Xianling Feng, Yuriko Mori and Stephen J Meltzer. Endoglin Promoter Hypermethylation Identifies a Field Defect in Human Primary Esophageal Cancer. Cancer，2013（Oct 15），119（20）3604-9.（共同第一作者）(IF：5.214, JCR分区大2小2)

3. Jin Z*, Wang L, Zhang Y, Cheng Y, Gao Y, Feng X, Dong M, Cao Z, Chen S, Yu H, Zhao Z, Zhang X, Liu J, Mori Y, Fan X, Meltzer SJ. MAL hypermethylation is a tissue-specific event that correlates with MAL mRNA expression in esophageal carcinoma. Sci Rep. 2013 Oct 3;3:2838. doi: 10.1038/srep02838.(IF:5.078，JCR分区大2小3）

4. Jin Z*, Feng X, Jian Q, Cheng Y, Gao Y, Zhang X, Wang L, Zhang Y, Huang W, Fan X, Chen S, Yu H, Zhao Z, Dong M, Liu J, Mori Y, Meltzer SJ. Aberrant Methylation of the Ras-related Associated with Diabetes Gene in Human Primary Esophageal Cancer. Anticancer Res. 2013 Nov;33(11):5199-203.(IF:1.872,JCR分区大4小4）

5. Zhe Jin, Liang Wang, Ziyi Cao, Yulan Cheng, Yan Gao, Xianling Feng, Si Chen, Huimin Yu, Wenjing Wu, Zhenfu Zhao, Ming Dong, Xiaojing Zhang, Jie Liu, Xinmin Fan, Yuriko Mori and Stephen J Meltzer. Temporal evolution in caveolin 1 methylation levels during human esophageal carcinogenesis. BMC Cancer. 2014,14:345-352.

6. Shuhua Mu, Jiachuan Wang, Guangqian Zhou, Wenda Peng, Zhendan He, Zhenfu Zhao, CuiPing Mo, Junle Qu*, Jian Zhang*. Transplantation of Induced Pluripotent Stem Cells Improves Functional Recovery in Huntington’s Disease Rat Model. PLOS ONE. 2014，9(7):1-10. (IF:3.534）

7.Sheng-lang Zhu, Peng-fei Wei, Jie-hui Chen, Zhen-fu Zhao, Qian-na Xu, Ling Ye. Diagnosis and treatment of a patient with Kimura’s disease associated with nephritic syndrome and lymphadenopathy of the epitrochlear nodes. BMC Nephrology. 2015, 16:10. Published online 2015 February 6. doi: 10.1186/s12882-015-0007-7  PMCID: PMC4363061

8. Chengang Song, Jiachuan Wang, Cuiping Mo, Shuhua Mu, Xiaogang Jiang, Xiaoyun Li, Shizhen Zhong*, Zhenfu Zhao*, Guangqian Zhou*. Use of Ferritin Expression, Regulated by Neural Cell-Specific Promoters in Human Adipose Tissue-Derived Mesenchymal Stem Cells, to Monitor Differentiation with Magnetic Resonance Imaging In Vitro. PLOS ONE. 2015，10(7):1-14. (IF:3.534）（e0132480. Published online 2015 July 15）（co-respongding author）

9. Xiaojing Zhang*, Yin Peng,*, Zhe Jin*, Weiling Huang, Yulan Cheng, Yudan Liu, Xianling Feng, Mengting Yang, Yong Huang, Zhenfu Zhao, Liang Wang, Yanjie Wei, Xinmin Fan, Duo Zheng, Stephen J. Meltzer. Integrated miRNA profiling and bioinformatics analyses reveal potential causative miRNAs in gastric adenocarcinoma. Oncotarget, 2015;6(32):32878-32889.

10. Jiuhong Li, Pengfei Wei P, Zhenfu Zhao, Meng Li, Jinwen Hua, Ni Xie, Xiaohua Xie, Shenglang Zhu, Kunmei Ji. Suggestions to improve medical education in China-learning from diagnostic errors of kidney diseases. Nephrology Open J. 2016; 2(1): 14-16. doi:  10.17140/NPOJ-2-113

11. Biao Yin, Yong Zeng, Tonghua Wu, Shuyi Yu, Jian Xu, Su Liu, Lianghui Diao, Zhenfu Zhao, Desheng Liang and Yuye Li. Functional properties of peripheral CD8+ T cells in patients with repeated implantation failure. American Journal of Reproductive Immunology. 2017, 78(2):12704-12709

D.   Research Support

Ongoing Research Support

Shenzhen Science and Technology Innovation Commission grant (No.CXZZ20140418182638770)                                                                                                             08/2014 to 08/2018

Zhenfu Zhao,                                                                            ￥1,150,000

Industrialization of cardiovascular disease eventuality prewarning diagnostic reagent

Guangdong province science and technology plan project (No.2016A020215176)

                                                                                            08/2016 to 07/2018

Zhenfu Zhao,                                                                            ￥100,000

The key-technique of Industrialization of early renal damage diagnostic reagent.

Completed Research Support

Guangdong Medical Science Fund(No.A2014511)                                                                                                                                                                                          06/2014 to 05/2016

Zhenfu Zhao,                                                               ￥5,000

The repaired function and mechanism research of the Shootin1 gene modified MSCs in Alzheimer’s disease.

Shenzhen Science and Technology Innovation Commission grant (No.JC200903120060A)                                                                                                            10/2009 to 09/2013

Zhenfu Zhao,                                                               ￥100,000

Empirical study of the biology and allergic mechanism of Tarsonemus

Guangdong province Educational scientific research project of “the 12th Five-year plan” (2012JK285)

                                                                              01/2013 to 12/2014

Zhenfu Zhao,                                                              

Study and practice of the innovative competence cultivation of medical students in new century.

E.  A ward s

2008.12，First prize, Advance of Science and Technology, Jiamusi city

2014.01，Second prize, Teaching Achievement of Higher Education, Guangdong province.

2015.06，Tencent Outstanding Teacher Award

2017.05，First prize, Teaching Achievement, Shenzhen University.