Wang, Xia (Assistant Professor)

Wang, Xia (Assistant Professor) Assistant Professor

Basic Medical School

Assistant Professor

Department of Anatomy, Histology & Developmental Biology

BIOGRAPHICAL SKETCH

NAME: Wang, Xia

POSITION TITLE: Assistant Professor;  Department of Anatomy, Histology & Developmental Biology, Shenzhen University School of Medicine

EDUCATION/TRAINING

INSTITUTION AND LOCATION

DEGREE

 

Completion Date

MM/YYYY

FIELD OF STUDY

 

Wuhan University of Science and Technology, China

B. Med

07/2002

Clinical Medicine

Huazhong University of Science and Technology, China

M.Sc.

07/2006

Neuroanatomy

The Chinese University of Hong Kong, China

Ph.D.

06/2009

Developmental Biology

The Chinese University of Hong Kong, China

Research Assistant

11/2010

Developmental Biology

Thomas Jefferson University, Philadelphia, USA

Thomas Jefferson University, Philadelphia, USA

Postdoctoral

Research Assistant

03/2016

05/2017

Developmental Biology

Developmental Biology

 

A.   Personal Statement

My long-standing research interests are in the pathogenesis of congenital disease associated with abnormal development of neural crest cells, such as Hirschsprung’s disease and congenital heart disease. I am a junior research scientist within Prof. Ou Sha’s laboratory at Shenzhen University. Our lab is focusing on the role of the extracellular matrix during the development of neural crest cells. I have published five first author/co-first author papers in professional, peer-reviewed journals including Gastroenterology, Developmental Biology and Development.

 

B.   Positions and Honors

Positions and Employment

06/2017 – present       Assistant Professor, Department of Anatomy, Histology & Developmental Biology, Shenzhen University School of Medicine, Shenzhen, China

 

Other Experience and Honors

1.    Jefferson Medical College Postdoctoral Travel Award: 2012

2.    2nd Runner-up in the ‘Art & Science of Imaging’ Cellular Imaging Competition, Hong Kong (organized by Invitrogen Hong Kong Limited): 2010

 

C.   Research Support

Ongoing Research Support

Shenzhen Science and Technology Innovation Commission grant                                   03/01/2018 to 03/31/2020

Xia Wang, PI                                                                                                                                     ¥480,000

The role of Integrin a5 in the pathogenesis of Congenital Heart Disease

 

Completed Research Support

American Heart Association Great Rivers Affiliate Winter 2012 Postdoctoral Fellowship (12POST11750033)                                                                        2012 to 2014

Xia Wang, PI                                                                                                          $91,000

Tissue specific role of fibronectin in the development of the cardiac neural crest cells

 

D.   Peer-reviewed publications (#: first author/co-first author; *: corresponding author)

 

  1. Wang, X#,*., & Astrof, S. (2017). Isolation of Mouse Cardiac Neural Crest Cells and Their Differentiation into Smooth Muscle Cells. Bio-Protocol7(17), e2530. http://doi.org/10.21769/BioProtoc.2530
  2. Wang X#, Chen D#, Chen K, Jubran A, Ramirez AJ and Astrof S*. (2017) Endothelium in the pharyngeal arches 3, 4 and 6 is derived from the second heart field. Developmental Biology Jan 15; 421 (2): 108-117
  3. Wang X# and Astrof S*. (2016) Neural crest cell-autonomous roles of fibronectin in cardiovascular development. Development. Jan 1; 143(1): 88-100.
  4. Chen D, Wang X#, Gordon J, Mittal A, Manley N, Degenhardt K, Astrof S*. (2015) Firbonectin signals through integrin Fibronectin signals through integrin α5β1 to regulate cardiovascular development in a cell type-specific manner.  Developmental Biology. Nov 15; 407(2): 195-210. (Co-first author)
  5. Liang D, Wang X, Mittal A, Dhiman S, Hou SY, Degenhardt K, Astrof S*. (2014) Mesodermal expression of integrin a5b1 regulates neural crest development and cardiovascular morphogenesis. Developmental Biology. 395(2): 232-244.
  1. Wang X#, Chan AKK, Sham MH, Burns AJ* and Chan WY*. (2011). Analysis of the sacral neural crest cell contribution to the hindgut enteric nervous system in the mouse embryo. Gastroenterology. 141 (3), 992-1002.
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