NAME: Li, Jianna

POSITION TITLE: Associate Professor, Shenzhen University School of Medicine

EDUCATION/TRAINING

A.   Personal Statement

My long-standing research interests fall in the molecular mechanisms of miRNAs in tumorigenesis and safety evaluation of biological materials in vivo. I graduated from Sun Yat-sen University and got my PhD degree in Biochemistry & Molecular Biology in July 2008.  I then worked as a Postdoctoral fellow for 3 years in Tsinghua University. I am now an Associate Professor  at Shenzhen University School of Medicine.

B.   Positions and Honors

Positions and Employment

0 6 /20 11 – present       Associate Professor , Shenzhen University , School of Medicine, Shenzhen, China

01/201 7 – present      Visiting Professor, Johns Hopkins University , School of Medicine , Maryland , USA

Other Experience and Honors

06/2010, High Level Professional Talents in Shenzhen, Shenzhen Municipal Human Resources and Social Security Bureau

C.   Contributions to Science (*: corresponding/co-corresponding author)

A full list of my publications (total of 10) is enclosed at the end of this document.

D.   Research Support

Ongoing Research Support

None

Completed Research Support

Shenzhen Basic Research Project( JCYJ20150324141711609 )                       08/2015-07/2017

Jianna Li                                                                                                              300,000

The regulatory effect and molecular mechanism of cluster miR-24/23b/27b on the development of lung cancer

Shenzhen Basic Research Project(20130319202328)                                        06/2013-12/2015

Jianna Li                                                                                                               100,000

 Study on the target gene and function of miR-96 in lung cancer

The Natural Science Foundation of Shenzhen University(201219)                         06/2012-06/2014

Jianna Li                                                                                                               50,000

Study on the mechanism of micro RNA regulating tumor cell cycle

Shenzhen Basic Research Project (JC201005310710A)                                       10/2010-09/2012

Jianna Li                                                                                                               50,000

Study of small nucleic acid candidates for inhibition of tumor angiogenesis and metastasis

China Postdoctoral Fund(20090450414),                                                             03/2009-02/2011

 Jianna Li                                                                                                              30,000

Inhibition of miRNA-X and its inhibitor on tumor metastasis

E.    publications (*: corresponding author)

Shiguo Chen, Yujuan Guo, Huanqiong Zhong, Shaojun Chen, Jianna Li（co-corresponding author）, Zaochuan Ge, Jiaoning Tang. Synergistic antibacterial mechanism and coating application of copper/titanium dioxide nanoparticles. Chemical Engineering Journal. 2014;256:238–246.

Liang He, JiannaLi , JohnH.Xin *. A novel grapheneoxide-based fluorescent nanosensor for selective detection of Fe3+ with a wide linear concentration and its application in logic gate. Biosensors and Bioelectronics.2015;

Yuxiang Chen , Jianna Li(Co-first author ), Qingqing Lia, Yuanyuan Shenb, Zaochuan Gea, Wenwen Zhangc, Shiguo Chen.Enhanced water-solubility, antibacterial activity and biocompatibility upon introducing sulfobetaine and quaternary ammonium to chitosan. Carbohydr Polym. 2016 Jun 5;143:246-253

Chen S, Yuan L, Li Q, Li J, Zhu X, Jiang Y, Sha O, Yang X, Xin JH, Wang J, Stadler FJ, Huang P. Durable Antibacterial and Nonfouling Cotton Textiles with Enhanced Comfort via Zwitterionic Sulfopropylbetaine Coating. Small. 2016 Jul;12 (26):3516-21

 Dan Zhu, Honghao Cheng, Jianna Li, Wenwen Zhang, Yuanyuan Shen , Shaojun Chen, Zaochuan Ge, Shiguo Chen, Enhanced water-solubility and antibacterial activity of novel chitosan derivatives modified with quaternary phosphonium salt. Mater Sci Eng C Mater Biol Appl. 2016 Apr 1;61:79-84

Li jianna and Liang Chun*, mRNA expression of the DNA replication-initiation proteins in epithelial dysplasia and squamous cell carcinoma of the tongue. BMC cancer，2008.8（395）:1-8.

Xie WD，Wang H，Zhang JF，Li JN，Can Y，Qing L，Kung HF，Zhang YO *，Enhanced peroxisomal β-oxidation metabolism in visceral adipose tissues of high-fat diet-fed obesity-resistant C57BL/6 mice，Experimental and Therapeutic Medicine，2011.2 (2):pp309.

Xie W，Gu D，Li J，Cui K，Zhang Y*，Effects and action mechanisms of berberine and Rhizoma coptidis on gut microbes and obesity in high-fat diet-fed C57BL/6J mice，PLoS One，2011.6 (9): pp24520.

He J，Zhang JF，Yi C，Xie WD，Li JN, Wan G，Cui K，Kung HF，Yang J, Yang BB, Zhang Y*，miRNA-mediated functional changes through co-regulating function related genes，PLoS ONE，2010.5 (10):pp13558.

He J, Wu J, Xu N, Xie W, Li M, Li J, Jiang Y, Yang BB, Zhang Y*， MiR-210 disturbs mitotic progression through regulating a group of mitosis-related genes. Nucleic Acids Res.，2012.41 (1):pp498.