NAME: Li, Ying

POSITION TITLE: Assistant Professor of physiopathology; Shenzhen University School of Medicine

EDUCATION/TRAINING

A.   Positions and Employment

0 8 / 2009 – 12 / 201 4        Assistant researcher , Shenzhen Institute of Advanced Technology (SIAT), Chinese Academy of Sciences, Shenzhen , China

01 /201 5 – 0 9 /201 5       Associate researcher , Shenzhen Institute of Advanced Technology (SIAT), Chinese Academy of Sciences, Shenzhen, China

10 /201 5 – 06 /2017      Senior researcher, Shenzhen University School of Medicine, Shenzhen University, Shenzhen, China

0 7 /201 7 – present        Assistant Professor of physiopathology, Shenzhen University School of Medicine, Shenzhen University, Shenzhen, China

B.   Research interests

Single-molecule imaging and detection

C.   Research Support

Completed Research Support

NSFC (China) (31400655)                                          01/01/2015 to 12/31/2017

Ying Li, PI                                                                        ￥250,000

Research on the molecular mechanism of FMRP-mediated translational repression through miRNA pathway

D.   Peer-reviewed publications (*: corresponding author ; ^#co-first author)

          (1)   Hu, Juan^（#）; Liu, Ming-hao^（#）; Li, Ying^（#）; Tang, Bo^（*）; Zhang, Chun-yang^（*）, Simultaneous sensitive detection of multiple DNA glycosylases from lung cancer cells at the single-molecule level, Chemical Science, 2018.1.21, 9(3)：712 ~ 720   

          (2)  Yang, Jie^（#）; Zhang, Rui^（#）; Jiang, Xin^（#）; Lv, Jingzhang; Li, Ying; Ye, Hongyu; Liu, Wenjuan; Wang, Gang; Zhang, Cuicui; Zheng, Na; Dong, Ming; Wang, Yan; Chen, Peiya; Santosh, Kumar; Jiang, Yong^（*）; Liu, Jie^（*）, Toll-like receptor 4-induced ryanodine receptor 2 oxidation and sarcoplasmic reticulum Ca(2+) leakage promote cardiac contractile dysfunction in sepsis., Journal of Biological Chemistry, 2018.1.19, 293(3)：794 ~ 807   

          (3)  Hu, Juan^（#）; Li, Yueying^（#）; Li, Ying^（#）; Tang, Bo^（*）; Zhang, Chun-Yang^（*）, Single Quantum Dot-Based Nanosensor for Sensitive Detection of O-GlcNAc Transferase Activity., Analytical Chemistry, 2017.12.5, 89(23)：12992 ~ 12999   

          (4)  Ma, Fei^（#）; Li, Ying^（#）; Tang, Bo^（*）; Zhang, Chun-Yang^（*）, Fluorescent Biosensors Based on Single-Molecule Counting., Accounts of Chemical Research, 2016.9.20, 49(9)：1722 ~ 1730   

          (5)  Li, Ying^（#）; Tang, Wei; Zhang, Li-rong; Zhang, Chun-yang^（*）, FMRP regulates miR196a-mediated repression of HOXB8 via interaction with the AGO2 MID domain., Mol Biosyst, 2014.7, 10(7)：1757 ~ 1764   

          (6)  Li, Ying^（#）; Liang, Li^（#）; Zhang, Chun-yang^（*）, Isothermally Sensitive Detection of Serum Circulating miRNAs for Lung Cancer Diagnosis, Analytical Chemistry, 2013.12.3, 85(23)：11174 ~ 11179   

          (7)  Zhu, Guichi^（#）; Li, Ying^（#）; Zhang, Chun-yang^（*）, Simultaneous detection of mercury(II) and silver(I) ions with picomolar sensitivity, Chemical Communications, 2014, 50(5)：572 ~ 574   

          (8)  Li, Ying^（#）; Zhang, Chun-yang^（*）, Analysis of MicroRNA-Induced Silencing Complex-Involved MicroRNA-Target Recognition by Single-Molecule Fluorescence Resonance Energy Transfer, Analytical Chemistry, 2012.6.5, 84(11)：5097 ~ 5102   

          (9)  Li, Xin^（#）; Cao, Jian-Hua^（#）; Li, Ying^（#）; Rondard,  Philippe; Zhang, Yang; Yi, Ping; Liu, Jian-Feng^（*）; Nan, Fa-Jun^（*）, Activity-based probe for specific photoaffinity labeling gamma-aminobutyric acid B (GABAB) receptors on living cells: design, synthesis, and biological evaluation, JOURNAL OF MEDICINAL CHEMISTRY, 2008.6.12, 51(11)：3057 ~ 3060   

       (10)  Rondard, Philippe^（#）; Huang, Siluo^（#）; Monnier, Carine; Tu, Haijun; Blanchard, Bertrand; Oueslati, Nadia; Malhaire, Fanny; Li, Ying; Trinquet, Eric; Labesse, Gilles; Pin, Jean-Philippe^（*）; Liu, Jianfeng^（*）, Functioning of the dimeric GABA(B) receptor extracellular domain revealed by glycan wedge scanning., The EMBO Journal, 2008.5.7, 27(9)：1321 ~ 1332