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基础医学院

林大川
助理教授


      林大川,香港理工大学博士,助理教授。主要从事医学微生物学教学,细菌耐药性分子流行病学,耐药机制探索及控制耐药细菌传播的研究。以第一作者发表细菌耐药研究相关SCI文章7篇,共同一作2篇。主持国家自然科学青年科学基金1项。


      主持项目:Atorvastatin增加结核分枝杆菌对乙胺丁醇敏感性作用和机制研究  81802060

 

代表成果:

(1) Ning Dong#, Dachuan Lin#, Rong Zhang , Edward Wai-Chi Chan and Sheng Chen*, Carriage of blaKPC-2 by a virulence plasmid in hypervirulent Klebsiella pneumonia, Journal of Antimicrobial Chemotherapy, 2018; 73: 3317–3321.

(2)Dachuan Lin, Kaichao Chen, Miaomiao Xie, Lianwei Ye, Eward Wai-Chi Chan, Sheng Chen*, Effect of ceftiofur and enrofloxacin on E. coli sub-population in pig gastrointestinal tract, Journal of Global Antimicrobial Resistance, 2017,10: 126-130.

(3)Dachuan Lin, Miaomiao Xie, Ruichao Li, Kaichao Chen, Chan EW-C, Sheng Chen*, IncFII conjugative plasmid-mediated transmission of blaNDM-1 elements among animal-borne E. coli strains, Antimicrobial Agents and Chemotherapy, 2017, 61(1):e02285-16.

(4)Dachuan Lin, Kaichao Chen, Chan EW-C,Sheng Chen*, Increasing prevalence of ciprofloxacin-resistant food-borne Salmonella strains harboring multiple PMQR elements but not target gene mutations Scientific reports, 2015, 5:14754.

(5)Dachuan Lin, Sheng Chen*, First detection of conjugative plasmid-borne fosfomycin resistance gene fosA3 in Salmonella isolates of food origin, Antimicrob Agents Chemother, 2015, 59(2): 1381-1383.

(6)Dachuan Lin, Kaichao Chen, Ruichao Li, Jiubiao Guo, Wen Yao, Sheng Chen*, Selection of target mutation in rat gastrointestinal tract E. coli by minute dosage of enrofloxacin, Front Microbiol, 2014, 5:468.

(7)Dachuan Lin, Meiying Yan, Song Lin, Sheng Chen*, Increasing prevalence of hydrogen sulfide negative Salmonella in retail meats, Food Microbiology. 2014, 43: 1-4.

(8)Jing Wang#,Dachuan Lin#, Xiao-Mu Guo, Hong-Kun Wei, Xiao-Qin Liu, Xiao-Jie Chen, Jian-Ying Guo, Zhen-Ling Zeng, and Jian–Hua Liu*, Distribution of the Multidrug Resistance Gene cfr in Staphylococcus Isolates from Pigs, Workers, and the Environment of a Hog Market and a Slaughterhouse in Guangzhou, China, Foodborne pathogens and disease, 2015, 12(7): 598-605.