Name：Mian Chen

Position：Associate Professor

E-mail：mian.chen@szu.edu.cn

Personal Statement:

Dr. Mian Chen received his Ph.D. in Analytical Chemistry from Hunan University in 2014, and then joined the Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences for postdoctoral training from 2014 to 2017. In 2017, he joined the College of Biomedical Engineering of Shenzhen University as an associate researcher. His primary research focuses on medical ultrasound, photoacoustic imaging, and nanomedicine, dedicated to developing novel imaging methods, engineering technologies, and functional nanomaterials to advance interdisciplinary applications in tumor diagnosis and treatment.

Research Interests:

l                      Medical ultrasound

l                      Photoacoustic imaging

Research Projects:

1.       NSFC (China) Project (81971637): Magnetic nanoprobes for targeted ultrasound elastographic imaging of liver cancer, 2020/01-2023/12, ￥550,000

2.       NSFC (China) Project (21505149): Construction and application of gold nanoprobes for photoacoustic imaging guided cancer targeted therapy, 2016/01-2018/12, ￥210,000

3.       Natural Science Foundation of Shenzhen City (JCYJ20170818141950351): Construction and application of multiferroic nanoprobes for multimodal molecular imaging of tumors, 2018/03-2020/09, ￥500,000

4.       Natural Science Foundation of Shenzhen City (20200826102024001): Physical mechanism and application research of microfluidic combined with acoustic manipulation of nanoparticles, 2021/01-2022/12, ￥200,000

5.       NSFC (China) Project (82327804): Ultrasound-electromagnetism coupled innovative targeted shear wave elastography and corresponding instrument development, 2024/01-2028/12, ￥7,287,500 (participation)

Selected Peer-reviewed Publications:

1.                      Xiangwei Lin#, Zhourui Xu#, Jiangao Li, Hongji Shi, Zhenyu Fu, Yuqing Chen, Wenguang Zhang, Yibin Zhang, Haoming Lin, Gaixia Xu, Xin Chen, Siping Chen and Mian Chen*. Visualization of photothermal therapy by semiconducting polymer dots mediated photoacoustic detection in NIR II. Journal of Nanobiotechnology, 2023, 21(01): 468.

2.                      Haoming Lin#, Tiemei Chen#, Dingqian Deng, Zhaoke Pi, Siyuan Xie, Ge Ding, Tingting Qi, Kaixin Shu, Xiangwei Lin, Zhourui Xu, Zhiyong Wang, Siping Chen, Mian Chen* and Xin Chen*. Magnetomotive ultrasound shear wave elastography (MMUS-SWE): a validation study from simulations to experiments. IEEE Transactions on Biomedical Engineering, 2023, 70(6): 1758-1767.

3.                      Xiangwei Lin*, Hongji Shi, Xiaozhou Fan, Jiaxin Wang, Zhenyu Fu, Yuqing Chen, Siping Chen, Xin Chen and Mian Chen*. Handheld interventional ultrasound/photoacoustic puncture needle navigation based on deep learning segmentation. Biomedical Optics Express, 2023, 14(11): 5979-5993.

4.                      Zhaoke Pi, Dingqian Deng, Xin Chen, Siping Chen, Haoming Lin and Mian Chen*. Magneto-acoustic theranostic approach: integration of magnetomotive ultrasound shear wave elastography and magnetic hyperthermia. Journal of Ultrasound in Medicine, 2024, 43(10), 1819-1831.

5.                      Mian Chen, Feiyan Cai, Chen Wang, Zhiyong Wang, Long Meng, Fei Li, Pengfei Zhang, Xin Liu, Hairong Zheng*, Observation of metal nanoparticles for acoustic manipulation. Advanced Science, 2017, 4(5): 1600447.