Name：Zida Li

Position：Associate Professor

E-mail：zidali@szu.edu.cn

Personal Statement:

Zida Li is a Tenured Associate Professor and Doctoral Supervisor. He obtained his Bachelor’s degree from the University of Science and Technology of China (USTC) in 2012, followed by short-term research training at The University of Hong Kong (HKU). He earned his Ph.D. from the University of Michigan, Ann Arbor, in 2018. Since 2018, he has been a faculty member at the School of Biomedical Engineering, Shenzhen University, and was promoted to Tenured Associate Professor in 2024.

Dr. Li’s interdisciplinary research spans microfluidics, molecular biology, and artificial intelligence, with a focus on single-molecule nucleic acid/immunoassay detection and single-cell sequencing. He has pioneered label-free digital nucleic acid amplification technologies, recognized for their groundbreaking innovation in academia. His work has been published in top-tier journals such as PNAS, Advanced Science, and Analytical Chemistry. He has received numerous grants and accolades, including the Baxter Young Investigator Award, Outstanding Oral Presentation at the Annual Analytical Chemistry Conference, grants from the National Natural Science Foundation of China, Guangdong Provincial Natural Science Foundation, and Shenzhen Medical Research Special Fund. Additionally, Dr. Li holds multiple patents in microfluidics and digital nucleic acid detection and leads industry-academia collaborative R&D projects. He actively contributes to the biomedical engineering community as a reviewer for leading international journals and an organizer of academic conferences. For collaboration opportunities, visit the group homepage: https://zidalab.github.io

Research Interests:

Digital Ultra-sensitive Nucleic Acid and Immunoassay Testing

Single-Cell RNA Sequencing

Microengineered Point-of-Care Testing

Research Projects:

1. National Natural Science Foundation of China (NSFC), 2024–2026, Principal Investigator

2. Guangdong Provincial Natural Science Foundation, 2019–2022, Principal Investigator

3. Shenzhen Medical Research Special Fund, 2025–2026, Principal Investigator

Selected Peer-reviewed Publications:

1. Meichi Jin,^# Jingyi Ding,^# Yu Zhou, Jiazhao Chen, Yi Wang, and Zida Li* (2024). StratoLAMP: Label-free, multiplex digital loop-mediated isothermal amplification based on visual stratification of precipitate. Proceedings of the National Academy of Sciences, 121(2), e2314030121

2. Linzhe Chen,^# Jingyi Ding,^# Hao Yuan, Chi Chen*, and Zida Li* (2022). deep-dLAMP: deep learning-enabled polydisperse emulsion-based digital loop-mediated isothermal amplification. Advanced Science, 9(9), 2105450

3. Kai Wu,^# Qi Fang,^# Zhantao Zhao, and Zida Li* (2023). CoID-LAMP: Color-encoded, intelligent digital LAMP for multiplexed nucleic acid quantification. Analytical Chemistry, 95(11), 5069–5078

4. Donghao Li,^# Xinyu Liu,^# Yujuan Chai,^# Jieying Shan, Yihan Xie, Yong Liang, Susu Huang, Weidong Zheng, and Zida Li* (2022). Point-of-care blood coagulation assay enabled by printed circuit board-based digital microfluidics. Lab on a Chip, 22(4), 1473-0197

5. Yi Zheng, Xufeng Xue, Yue Shao, Sicong Wang, Sajedeh Nasr Esfahani, Zida Li, Jonathon M. Muncie, Johnathon N. Lakins, Valerie M. Weaver, Deborah L. Gumucio, and Jianping Fu (2019). Controlled modeling of human epiblast and amnion development using stem cells. Nature, 573(7774), 421-425