Name：Zhaohan Wei

Position：Assistant Professor

E-mail：weizhaohan@szu.edu.cn

Personal Statement:

Dr. Zhaohan Wei received his Ph.D. degree and undertook postdoctoral work at Huazhong University of Science and Technology. In 2025, Dr. Wei joined the School of Biomedical Engineering of Shenzhen University Medical School as an assistant professor. His research focuses on bioinspired nanomaterials and tumor immunotherapy.

Over the past five years, Dr. Wei has published 18 peer-reviewed articles in prestigious international journals including Nature Communications, Advanced Materials, Signal Transduction and Targeted Therapy, Journal of Controlled Release, and Chemical Engineering Journal. He currently serves as Principal Investigator for research projects including the National Natural Science Foundation of China (NSFC) and China Postdoctoral Science Foundation.

Research Interests:

Bioinspired nanomaterials

Tumor immunotherapy

Research Projects:

1. NSFC (China) Project (82203061):  01/2023 to 12/2024  ￥200,000

2. China Postdoctoral Science Foundation (2022M721260):  10/2022 to 10/2023 ￥80,000

Selected Peer-reviewed Publications:

1. Zhaohan Wei#, Xiaoqiong Zhang#, Tuying Yong, Nana Bie, Guiting Zhan, Xin Li, Qingle Liang, Jianye Li, Jingjing Yu, Gang Huang, Yuchen Yan, Zelong Zhang, Bixiang Zhang, Lu Gan*, Bo Huang*, Xiangliang Yang*. Boosting anti-PD-1 therapy with metformin-loaded macrophage-derived microparticles. Nature Communications, 2021, 12(1): 440

2. Zhaohan Wei#, Xiaoqiong Zhang#, Zelong Zhang#, Tuying Yong, Guiting Zhan, Weilin Lv, Ziqiao Ding, Kaili Sun, Xiangliang Yang*, Lu Gan*. Engineered iron-based nanoplatform amplifies repolarization of M2-like tumor-associated macrophages for enhanced cancer immunotherapy. Chemical Engineering Journal, 2022, 433: 133847

3. Xiaoqiong Zhang#, Zhaohan Wei#, Tuying Yong#,  Shiyu Li, Nana Bie, Jianye Li, Xin Li, Haojie Liu, Hang Xu, Yuchen Yan, Bixiang Zhang, Xiaoping Chen, Xiangliang Yang*, Lu Gan*. Cell microparticles loaded with tumor antigen and resiquimod reprogram tumor-associated macrophages and promote stem like CD8+ T cells to boost anti-PD-1 therapy. Nature Communications, 2023, 14(1): 5653

4. Nana Bie#, Tuying Yong#, Zhaohan Wei#, Qingle Liang, Xiaoqiong Zhang, Shiyu Li, Xin Li, Jianye Li, Lu Gan*, Xiangliang Yang*. Tumor-repopulating cell-derived microparticles elicit cascade amplification of chemotherapy-induced antitumor immunity to boost anti-PD-1 therapy. Signal Transduction and Targeted Therapy, 2023, 8(1): 408

5. Xiaoqiong Zhang#, Zhaohan Wei#, Ziqiao Ding, Weilin Lv, Jianye Li, Xin Li, Haojie Liu, Panli Yu, Xiangliang Yang*, Lu Gan*. Boosting doxil-based chemoimmunotherapy via reprogramming tumor-associated macrophages. Chemical Engineering Journal, 2023, 451: 138971