Siping Chen, PhD

School of Biomedical Engineering, Shenzhen University, Shenzhen, China

Tel: (86)755-26536718, Email: chensiping@szu.edu.cn

Education

1978-1982, B.S. in Automation, Electronic University of Jiangxi

1982-1987, M.S. and Ph.D. in Biomedical Engineering, Xi'an Jiaotong University

Professional Experience

1987-1989,   Postdoctoral Fellowship, Zhejiang University

1989-2005, Chief Executive Engineer, Shenzhen Anke High-tech Co., Ltd

2005-2011, Vice president, Shenzhen University

2005-,      Founding Chair Professor, School of Biomedical Engineering, Shenzhen University

2011-2015, Laboratory Chief, Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging

2011-,    Laboratory Chief, National-Regional Key Technology Engineering Laboratory for Medical Ultrasound,

Honors and Awards

1994-,    Special Allowance Expert of the State Council

1994,   National Young Experts with Outstanding Contributions

1994,   National Prize for Progress in Science and Technology

2005,   Experts with outstanding contribution to Guangdong province

2012,       Distinguished Expert in Biomedical Ultrasound, Chinese Association of Ultrasound in Medicine and Engineering

National and International Committees and Boards

2005-,   Advisor of Ph. D. candidates in Zhejiang University

2005-,   Deputy director, National Technical Committee on Medical Electrical

Equipment of Standardization Administration of China as well as of

Ultrasound Sub-T

2005-,  Vice President, Chinese Association of Ultrasound in Medicine and Engineering

2010-,   Committee Member, National Key Basic Research Program of China (973 Program)

2014-,   IEC/TC87 WG member in China

Major Research Grants (cumulative budget of > RMB 45 million)

1.      Collaborative Innovation Center in Medical Instrument, National Development and Reform Commission, 2015-2018, RMB 16 million.

2.      National Natural Science Foundation of China, Major program (61427806), 2015.1-2019.12, RMB 4.95 million.

3.      National Natural Science Foundation of China, Key program (61031003), 2009.1-2014.12, RMB 2.60 million

4.      National Natural Science Foundation of China, General program (61372006), 2014.1-2017.12, RMB 0.80 million.

Selected Publications

1.        Zhu Y, Chen X, Zhang X, Chen S, Shen Y, Song L (2016) Modeling the mechanical properties of liver fibrosis in rats. Journal of Biomechanics 49: 1461-1467

2.        Lin H, Zhang X, Shen Y, Zheng Y, Guo Y, Zhu Y, Diao X, Wang T, Chen S, Chen X (2016) Model-dependent and model-independent approaches for evaluating hepatic fibrosis in rat liver using shearwave dispersion ultrasound vibrometry. Medical Engineering & Physics

3.        Lin H, Shen Y, Chen X, Zhu Y, Zheng Y, Zhang X, Guo Y, Wang T, Chen S (2016) Viscoelastic properties of normal rat liver measured by ultrasound elastography: Comparison with oscillatory rheometry. Biorheology

4.        Lei B, Chen S, Ni D, Wang T, Alzheimer's Dis N (2016) Discriminative Learning for Alzheimer's Disease Diagnosis via Canonical Correlation Analysis and Multimodal Fusion. Frontiers in Aging Neuroscience 8

5.        Guo Y, Dong C, Lin H, Zhang X, Wen H, Shen Y, Wang T, Chen S, Liu Y, Chen X (2016) Ex vivo study of acoustic radiation force impulse imaging elastography for evaluation of rat liver with steatosis. Ultrasonics 74: 161-166

6.        Du Y, Fan R, Li Y, Chen S, Jensen JA (2016) A framework for simulating ultrasound imaging based on first order nonlinear pressure-velocity relations. Ultrasonics 69: 152-165

7.        Chen X, Wen H, Li Q, Wang T, Chen S, Zheng Y-P, Zhang Z (2016) Identifying transient patterns of in vivo muscle behaviors during isometric contraction by local polynomial regression. Biomedical Signal Processing and Control 24: 93-102

8.        Zhu Y, Dong C, Yin Y, Chen X, Guo Y, Zheng Y, Shen Y, Wang T, Zhang X, Chen S (2015) The role of viscosity estimation for oil-in-gelatin phantom in shear wave based ultrasound elastography. Ultrasound in Medicine and Biology 41: 601-609

9.        Zhang X, Yin Y, Guo Y, Fan N, Lin H, Liu F, Diao X, Dong C, Chen X, Wang T, Chen S (2015) Measurement of quantitative viscoelasticity of bovine corneas based on lamb wave dispersion properties. Ultrasound in Medicine and Biology 41: 1461-1472

10.    Youyi S, Ling Z, Siping C, Dong N, Baiying L, Tianfu W (2015) Accurate segmentation of cervical cytoplasm and nuclei based on multiscale convolutional network and graph partitioning. IEEE Transactions on Biomedical Engineering 62: 2421-2433

11.    Xu M, Wang T, Chen S, Fox PT, Tan LH (2015) Effective connectivity of brain regions related to visual word recognition: An fMRI study of Chinese reading. Human Brain Mapping 36: 2580-2591

12.    Xin C, Qiaoliang L, Suwen Q, Huisheng Z, Siping C, Tianfu W (2015) Continuous fascicle orientation measurement of medial gastrocnemius muscle in ultrasonography using frequency domain Radon transform. Biomedical Signal Processing and Control 20: 117-124

13.    Peng X, Peng J, Tang H, Wang T, Chen S (2015) Ultrahigh Frequency Micromachined Ultrasound Transducers Based on Piezoelectric Single Crystalline Wafers. Journal of Medical Imaging and Health Informatics 5: 374-377

14.    Lei B, Yao Y, Chen S, Li S, Li W, Ni D, Wang T (2015) Discriminative Learning for Automatic Staging of Placental Maturity via Multi-layer Fisher Vector. Scientific Reports 5

15.    Lei B, Tan E-L, Chen S, Zhuo L, Li S, Ni D, Wang T (2015) Automatic Recognition of Fetal Facial Standard Plane in Ultrasound Image via Fisher Vector. Plos One 10

16.    Hu T, Jue P, Wenjuan W, Xiaojian P, Tianfu W, Siping C (2015) High-Curie-temperature relaxor piezoelectric single crystals for 1.5D ultrasound phased-array applications. Materials Letters 145: 258-260

17.    Chen X, Li Q, Qi S, Zhang H, Chen S, Wang T (2015) Continuous fascicle orientation measurement of medial gastrocnemius muscle in ultrasonography using frequency domain Radon transform. Biomedical Signal Processing and Control 20: 117-124

18.    Baiying L, Feng Z, Ee-Leng T, Dong N, Haijun L, Siping C, Tianfu W (2015) Optimal and secure audio watermarking scheme based on self-adaptive particle swarm optimization and quaternion wavelet transform. Signal Processing 113: 80-94

19.    Baiying L, Ee-Leng T, Siping C, Dong N, Tianfu W (2015) Saliency-driven image classification method based on histogram mining and image score. Pattern Recognition 48: 2567-2580

20.    Yu H, Xu L, Chen S (2014) A transfer efficiency model for ultrasound mediated drug/gene transferring into cells. Ultrasonics Sonochemistry 21: 113-120

21.    Ying Z, Xinyu Z, Yi Z, Xin C, Yuanyuan S, Haoming L, Yanrong G, Tianfu W, Siping C (2014) Quantitative analysis of liver fibrosis in rats with shearwave dispersion ultrasound vibrometry: comparison with dynamic mechanical analysis. Medical Engineering & Physics 36: 1401-1407

22.    Song Y, Ni D, Zeng Z, He L, Chen S, Lei B, Wang T (2014) Automatic Vaginal Bacteria Segmentation and Classification Based on Superpixel and Deep Learning. Journal of Medical Imaging and Health Informatics 4: 781-786

23.    Ni D, Yang X, Chen X, Chin C-T, Chen S, Heng PA, Li S, Qin J, Wang T (2014) Standard plane localization in ultrasound by radial component model and selective search. Ultrasound in Medicine and Biology 40: 2728-2742

24.    Jue P, Wenjuan W, Hu T, Tianfu W, Siping C (2014) Fabrication and performance of a 64 times 5 element 1.5D active matrix array transducer for medical imaging. Sensors and Actuators A (Physical) 214: 81-87

25.    Hao Y, Liang X, Siping C (2014) A transfer efficiency model for ultrasound mediated drug/gene transferring into cells. Ultrasonics Sonochemistry 21: 113-120

26.    Baiying L, Ee-Leng T, Siping C, Dong N, Tianfu W, Haijun L (2014) Reversible watermarking scheme for medical image based on differential evolution. Expert Systems with Applications 41: 3178-3188

27.    Baiying L, Dong N, Siping C, Tianfu W, Feng Z (2014) Optimal image watermarking scheme based on chaotic map and quaternion wavelet transform. Nonlinear Dynamics 78: 2897-2907

28.    Yi Z, Aiping Y, Shigao C, Urban MW, Haoming L, Xin C, Yanrong G, Ke C, Tianfu W, Siping C (2013) Ultrasound vibrometry using orthogonal- frequency-based vibration pulses. IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control 60: 2359-2370

29.    Sun Y, Wang T, Chen S, Zuo J, Zhang Z, Zhang C (2013) Impact of dynamical hydration shell around ha protein on nonlinear concentration dependent T-rays absorption. Journal of Innovative Optical Health Sciences 6

30.    Shen Y, Wang T, Chin C, Diao X, Chen S (2013) Interaction between microbubble and elastic microvessel in low frequency ultrasound field using finite element method. Chinese Science Bulletin 58: 291-298

31.    Qiaoliang L, Huisheng Z, Suwen Q, Mingbo Q, Xin C, Siping C, Tianfu W (2013) Continuous Detection of Muscle Aspect Ratio Using Keypoint Tracking in Ultrasonography. IEEE Transactions on Biomedical Engineering 60: 2361-2369

32.    Li Q, Qi S, Zhang H, Deng Y, Chen X, Chen S, Wang T (2013) Continuous thickness measurement of rectus femoris muscle in ultrasound image sequences: A completely automated approach. Biomedical Signal Processing and Control 8: 792-798

33.    Li Q, Ni D, Yi W, Chen S, Wang T, Chen X (2013) Use of optical flow to estimate continuous changes in muscle thickness from ultrasound image sequences. Ultrasound in Medicine and Biology 39: 2194-2204

34.    Hu Z, Zhang H, Yuan J, Lu M, Chen S, Liu H (2013) An H-infinity Strategy for Strain Estimation in Ultrasound Elastography Using Biomechanical Modeling Constraint. Plos One 8

35.    Chen X, Shen Y, Zheng Y, Lin H, Guo Y, Zhu Y, Zhang X, Wang T, Chen S (2013) Quantification of liver viscoelasticity with acoustic radiation force: a study of hepatic fibrosis in a rat model. Ultrasound in Medicine and Biology 39: 2091-2102

36.    Zhang L, Chen S, Chin CT, Wang T, Li S (2012) Intelligent scanning: Automated standard plane selection and biometric measurement of early gestational sac in routine ultrasound examination. Medical Physics 39: 5015-5027

37.    Yu H, Chen S, Cao P (2012) Synergistic bactericidal effects and mechanisms of low intensity ultrasound and antibiotics against bacteria: A review. Ultrasonics Sonochemistry 19: 377-382

38.    Wang Y, Chen S, Wang T, Zhou T, Li Q, Zheng Y, Chen X (2012) Development of a generic ultrasound vibro-acoustic imaging platform for tissue elasticity and viscosity. Journal of Innovative Optical Health Sciences 5

39.    Sun Y, Zhu Z, Chen S, Balakrishnan J, Abbott D, Ahuja AT, Pickwell-MacPherson E (2012) Observing the Temperature Dependent Transition of the GP2 Peptide Using Terahertz Spectroscopy. Plos One 7

40.    Ling Z, Siping C, Chien Ting C, Tianfu W, Shengli L (2012) Intelligent scanning: Automated standard plane selection and biometric measurement of early gestational sac in routine ultrasound examination. Medical Physics 39: 5015-5027

41.    Hao Y, Siping C, Ping C (2012) Synergistic bactericidal effects and mechanisms of low intensity ultrasound and antibiotics against bacteria: a review. Ultrasonics Sonochemistry 19: 377-382

42.    Cui Y, Peng J, Tang H, Wang T, Chen S (2012) New focused ultrasound transducer for fat cell disruption. Journal of Innovative Optical Health Sciences 5

43.    Huang Q, Zheng Y, Lu M, Wang T, Chen S (2009) A new adaptive interpolation algorithm for 3D ultrasound imaging with speckle reduction and edge preservation. Computerized Medical Imaging and Graphics 33: 100-110