BIOGRAPHICAL SKETCH

NAME：Dong, Haifeng

POSITION TITE: Distinguished Professor, Vice Dean of Research Centre for Biosensors and Nanotheranostics of Shenzhen University

EDUCATION/TRAINING：

Nanjing University, China, Ph.D, 06/2011, Analytical Chemistry

Chongqing University, China, M.Sc., 07/2008, Inorganic Chemistry

Sanxia University, China, Bachelor, 07/2005, Biological Engineering

A. Personal statement

Researches focus on nucleic acid biosensors and nano-medicines by the combination of biological technology and nanotechnology. Our group target the key issue of developing nucleic acids novel detection strategies as the main research theme, and research progresses have been achieved: (1) By the combining of novel nanotechnology and biological technology to make innovative contributions to detection principles and signal amplification strategies and develop highly sensitive, multiplex or label-free electrochemcial and optical DNA and miRNA analysis strategies. (2) Fabricating multi-functional nanoprobes for cell recogition, imaging, detection and regulation of intracellur miRNA. (3) We employ top-down or bottom-up methods to fabricate nanomaterials with unique physiochemical properties, which will be further modified functional moieties to impart new properties to design multi-functional theranostics nanosystems. I have published more than 100 SCI papers in Chem. Rev. Nat. Commun., Angew. Chem. Int. Ed.，Adv. Mater.，Nano Lett, ACS nano, et al, cited 5000 times by other scientists. He also published two books about the nucleic acids detection and editor one book about the bioapplication of nanomaterials.

B. Positions and Honors

Shen Zhen University, Professor, Sep. 2020

University of Science & Technology Beijing, Professor, Oct. 2013

Kyoto University, Visiting professor, July-Oct. 2015

University of Pittsburgh, Postdoctoral Researcher, Oct. 2012- Sep. 2013

University of Science & Technology Beijing, Associate Researcher (lecturer), July 2011- Oct. 2012

Honors

China National Funds for Outstanding Young Scientists in 2020.

The Second Class Natural Science Prize by Education Ministry of China in 2018

The First Class Scientific and Technological Prize by Chinese Association for Instrumental Analysis in 2018

National excellent 100 doctoral dissertation award nomination in 2013

Ph.D. thesis was named as the excellent Ph.D thesis of Jiangsu province. May, 2012

C. Representative publications

1.Yiyi Zhang, Yaru Cheng, Fan Yang, Zhipeng Yuan, Wei Wei, Huiting Lu∗, Haifeng Dong∗, Xueji Zhang. Near-Infrared Triggered Ti3C2/g-C3N4 Heterostructure for Mitochondria-Targeting Multimode Photodynamic Therapy Combined Photothermal Therapy. Nano Today 2020, 34, 100919

2.Conghui Liu, Yu Cao, Yaru Cheng, Dongdong Wang, Tailin Xu, Lei Su, Xueji Zhang*, Haifeng Dong*. An Open Source and Reduce Expenditure ROS Generation Strategy for Chemodynamic/ Photodynamic Synergistic Therapy. Nature Communications. 2020, 11, 1, 1735 

3.Shah Zada, # Wenhao Dai,# Zhang Kai, Huiting Lu, Xiangdan Meng, Yiyi Zhang, Yaru Cheng, Fang Yan, Pengcheng Fu, Xueji Zhang, * Haifeng Dong.* Algae Extraction Controllable Delamination of Vanadium Carbide Nanosheets with Enhanced Near-Infrared Photothermal Performance. Angew. Chem. Int. Ed. 2020, 59 (16), 6601-6606

4.Yanming Zhao⁺ , Wenhao Dai⁺ , Yunlei Peng, Zheng Niu, Qi Sun, Chuan Shan, Hui Yang, Gaurav Verma, Lukasz Wojtas, Daqiang Yuan, Zhenjie Zhang,* Haifeng Dong,* Xueji Zhang,* Bao Zhang,* Yaqing Feng, and Shengqian Ma* A Corrole-Based Covalent Organic Framework Featuring Desymmetrized Topology. Angew. Chem. Int. Ed. 2020, 59, 4354 –4359

5.Yaru Cheng, Fan Yang, Kai Zhang, Yiyi Zhang, Yu Cao, Conghui Liu, Huiting Lu, Haifeng Dong,* and Xueji Zhang. Non-Fenton-Type Hydroxyl Radical Generation and Photothermal Effect by Mitochondria-Targeted WSSe/MnO₂ Nanocomposite Loaded with Isoniazid for Synergistic Anticancer Treatment. Adv. Funct. Mater. 2019, 29(45), 1903850

6.Fan Yang, Yaru Cheng,Yu Cao, Yiyi Zhang, Haifeng Dong*, Huiting Lu, Xueji Zhang. MicroRNA Triggered DNA “Nano Wheel” for Visualizing Intracellular microRNA via Localized DNA Cascade Reaction. Analytical Chemistry, 2019, 91, 15, 9828-9835.

7.Kai Zhang, Xiangdan Meng, Zhou Yang, Yu Cao, Yaru Cheng, Dongdong Wang, Huiting Lu, Zhuojie Shi, Haifeng Dong* and Xueji Zhang Cancer Cell Membrane Camouflaged Nanoprobe for Catalytic Ratiometric Photoacoustic Imaging of MicroRNA in Living Mice. Advanced Materials 2019, 39(11), e1807888

8.Yaru Cheng, Fan Yang, Guolei Xiang, Kai Zhang, Yu Cao, Dongdong Wang, Haifeng Dong* and Xueji Zhang.* Ultrathin Tellurium Oxide/Ammonium Tungsten Bronze Nanoribbon for Multimodality Imaging and Second Near-Infrared Region Photothermal Therapy. Nano letters 2019, 19, 1179-1189 

9.Dongdong Wang, Haifeng Dong *, Meng Li, Yu Cao, Fan Yang, Kai Zhang, Wenhao Dai, Changtao Wang, Xueji Zhang * Erythrocyte−cancer hybrid membrane camouflaged hollow copper sulfide nanoparticles for prolonged circulation life and homotypic-targeting photothermal/ chemotherapy of melanoma. ACS Nano, 2018, 12 (6), 5241-5252

10.Haifeng Dong, Jianping Lei, Lin Ding, Yongqiang Wen, Huangxian Ju* and Xueji Zhang*. MicroRNA: Function, Detection, and Bioanalysis. Chemical Reviews 2013, 113(8), 6207-6233.

D. Research support

Ongoing projects (RMB)

1.China National Funds for Outstanding Young Scientists (22022407) 2021-01 to 2023-12

Haifeng Dong, PI             ￥ 1，200，000

microRNA in situ analysis

2.National Key R&D Program of China （2019YFC1606603）2019-12 to 2022-12

Haifeng Dong, PI             ￥ 1，248，600

Device study of monitoring and testing equipment for food corruption and mildew

3.NSFC (China) General Projects (21874008), 2019-01 to 2022-12

Haifeng Dong, PI             ￥ 640，000

Nucleic Acids analysis used 2D Mxene nanoprobe