BIOGRAPHICAL SKETCH

NAME: Hequn Zou

POSITION TITLE: Professor of Nephrology, Chief Doctor, Tutor of Doctor Candidates

EDUCATION/TRAINING

A. Personal statement

Hequn Zou, is Level 2 Professor/Chief Physician, Doctoral Supervisor, and German Medical Doctor. He is mainly engaged in kidney disease research. He has undertaken more than 30 scientific research projects, including more than 10 national and international cooperative scientific research projects, with total project funding of more than 40 million yuan. He has published more than 300 papers, including more than 70 SCI papers (three in JCR area 1, nine in JCR area 2). He has also applied for nine patents, including five authorized utility model patents.

B. Positions and honors

Positions

2018-presentPresident, Guangdong-Hongkong-Marco Great Bay League of Non-communicable Diseases

2018-presentPresident, Guangdong-Hongkong-Marco Great Bay League for Plasmapheresis

2018-presentPresident, Guangdong Provincial Society of NCD Prevention and Treatment

2017-presentPresident, Guangdong Provincial Society for Plasmapheresis

2017-presentChairman, Asia-Pacific Medical Bio-Immune Association of Nephrology

2017-presentPresident, Guangdong Provincial Society of Plasmapheresis

2014-presentCommittee Member, Chinese Medical Association of Internal Medicine

2012-presentVice-Chairman, Chinese Medical Doctor Association of Plasmapheresis

2011-presentVice-Chairman, Guangdong Provincial Medical Association of Internal Medicine

2010-presentStanding committee member, Guangdong Provincial Medical Association of Rheumatology

2010-presentEditor, Chinese Journal of Clinical Doctors

2006-presentDeputy Editor, Journal of Transplant Medicine

2004-presentVice-Editor, International Journal of Nephrology and Urology (Chinese)

2003-presentStanding Commissioner, Guangdong Provincial Science Administration Committee

2003-presentConsultant, Guangdong Provincial Medical Accident Appraisal Committee

2001-presentStanding Editor, Chinese Journal of Clinical Nephrology

2004-2009Commissioner, Guangdong Provincial Medical Association

2004-2008Committee Member, ISN-COMGAN Research and Prevention Committee

2004-2007Editor, Chinese Journal of Nephrology

2003-2008 Vice-Chairman, Guangdong Provincial Medical Association of Nephrology

2003-2007 Secretary General, Chinese Blood Purification Administration Committee

2002-2009 Commissioner, Guangdong Medical Doctors Association

2002-2008 Standing Editor, Chinese Journal of Blood Purification

Honors

2012Excellent Teacher, Southern Medical university

2011Excellent Teacher, Southern Medical university

2004First-class Award of Scientific and Technique Achievement, Zhuhai City

2003Provincial Excellent Scholar, Guangdong Province

2002National Excellent Young Teacher, Chinese Ministry of Education

2000 National Excellent Teacher, Chinese Ministry of Education

1996 Provincial Excellent Scholar, Guangdong Province

1994 Excellent Teacher, Guangdong Medical College

1994 Excellent Young Researcher, Guangdong Medical College

1993 ISN’s Fellowship Training Award, ISN

1991 Excellent Paper, Chinese Association of Medicine

C. Representative publications (selected publications in last 5 years; 5–10)

1.Deng J, Xia Y, Zhou Q, Wang X, Xiong C, Shao X, Shao M, Zou H*. Protective effect of rosiglitazone on chronic renal allograft dysfunction in rats. Transplant Immunology. 2019;54:20-28.

2.Chen H, Xiong C, Shao X, Ning J, Gao P, Xiao H, Chen Y, Zou Z, Hong G, Li X, Shao M, Sheng J, Yang X, You X, Zou H*. Lymphocyte to high-density lipoprotein ratio as a new indicator of inflammation and metabolic syndrome. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 2019;12:2117–2123.

3.Chen Y, Hong G, Wu F, Sheng J, Zou Z, Xiong C, Zhang Y, Deng J, Tang H, Wang X, Zou H*. Comparison of Hydrostatic Filtration Dialysis with Ultracentrifugation Methods for the Identification and Proteomic Profiling of Urinary Extracellular Vesicles. Clinical Laboratory. 2019;65(4):575-586.

4.Xu X, Liu X, Liu A, Wang X, Huang M, Zou H*. Proteomic analysis of the rest filtered protein after double filtration plasmapheresis. International Journal of Clinical and Experimental Medicine. 2018;11(9):9715.

5.Lv D, Zhou Q, Xia Y, You X, Zhao Z, Li Y, Zou H*. The association between oxidative stress alleviation via sulforaphane-induced Nrf2- HO-1/NQO-1 signaling pathway activation and chronic renal allograft dysfunction improvement. Kidney Blood Press Res. 2018;43:191-205.

6.Xia Y, Deng J, Zhou Q, Shao X, Yang X, Sha M, Zou H*. Expression and significance of Sirt1 in renal allografts at the early stage of chronic renal allograft dysfunction. Transpl Immunol. 2018 Feb 13.

7.Zhou Q, Lv D, Xia Y, Zhao Z, Zou H*. Decreased expression of sirtuin 3 protein correlates with early stage chronic renal allograft dysfunction in a rat kidney model. Exp Ther Med. 2018 Apr;15(4):3725-3732.

8.Hu S, Musante L, Tataruch D, Xu X, Kretz O, Henry M, Meleady P, Luo H, Zou H*, Jiang Y, Holthofer H. Purification and Identification of Membrane Proteins from Urinary Extracellular Vesicles using Triton X-114 Phase Partitioning. J Proteome Res. 2018;17(1):86-96.

9.Yan Q, Luo H, Wang B, Sui W, Zou G, Chen H, Zou H*. Correlation between PKB/Akt, GSK-3β expression and tubular epithelial-mesenchymal transition in renal allografts with chronic active antibody-mediated rejection. Exp Ther Med. 2017;13(5):2217-2224.

10.Ene-Iordache B, Perico N, Bikbov B, Carminati S, Remuzzi A, Perna A, Islam N, Bravo RF, Aleckovic-Halilovic M, Zou H, Zhang L, Gouda Z, Tchokhonelidze I, Abraham G, Mahdavi-Mazdeh M, Gallieni M, Codreanu I, Togtokh A, Sharma SK, Koirala P, Uprety S, Ulasi I, Remuzzi G. Chronic kidney disease and cardiovascular risk in six regions of the world (ISN-KDDC): a cross-sectional study. Lancet Glob Health. 2016;4(5):e307-19.

D. Research support

Ongoing projects (RMB)

1.Science and Technique Program of Guangzhou (No. 201604020015), 2016-2018, Hequn Zou, ￥4,000,000

2.Risk factors and prediction model of chronic kidney disease caused by metabolic syndrome: A multicentric prospective cohort study Clinical trial training project of Southern Medical University (No. LC2016PY047), 2016-2020, Hequn Zou, ￥400,000

3.South Wisdom Valley Innovative Research Team Program (No. CXTD-004), 2015-2019, Hequn Zou, ￥12,000,000

4.The National Nature Science Foundation of China (No. 81873620), 2019-2022, Hequn Zou, ￥700,000