Name：Tingting Xu

Position：Assistant Professor

E-mail：xutingting@szu.edu.cn

Personal Statement:

Dr Tingting Xu conducted her research and received her Ph.D. in microbiology from Ocean University of China. She was appointed as a Postdoctoral fellow at Nankai University in 2016, where she pioneered studies on the molecular pathogenesis of clinically relevant bacterial pathogens. In 2019, Dr Xu joined Shenzhen People’s Hospital as a research assistant, focusing on antibiotic resistance and pathogenesis research. In 2025, Dr Xu joined the Medical School of Shenzhen University as an assistant professor. Dr Xu specializes in molecular microbiology, especially in molecular bacterial pathogenesis and antibiotic resistance mechanisms, with several publications in high-impact academic journals including Lancet Microbe, Nature Communications, Emerging Microbes & Infections, etc.

Research Interests:

Bacterial Pathogenesis & Infection Control

Antibiotic resistance mechanisms

Research Projects:

1. NSFC (China) Project (81902030):  01/01/2020 to 12/31/2022  ￥200,000

2. Guangdong Basic and Applied Basic Research Foundation (2024A1515030182) 01/01/2024 to 12/31/2026 ￥300,000

3. Shenzhen Science and Technology Program (JCYJ20210324113608022):11/02/2021-10/31/2024  ￥300,000

4. Shenzhen Science and Technology Program (JCYJ20240813104159050):11/24/2024-11/26/2027  ￥300,000

Selected Peer-reviewed Publications:

1.Xu T, Xue C, Huang J, Wu J, Chen R, Zhou K^*. Emergence of an epidemic hypervirulent clone of Enterobacter hormaechei coproducing MCR-9 and carbapenemases. Lancet Microbe, 2022, 3(7):e474-e475.

2. Xu T, Guo Y, Ji Y, Wang B^*, Zhou K^*. Epidemiology and mechanisms of Ceftazidime-Avibactam resistance inGram-Negative bacteria. Engineering, 2022, 11:138-145.

3. Xu T^#, Xue C ^#, Chen Y^#, Huang J, Wu W, Lu Y, Huang Q, Chen D, Zhou K^*. Frequent convergence of mcr-9 and carbapenemase genes in Enterobacter cloacae complex driven by epidemic plasmids and host incompatibility. Emerg Microbes Infec, 2022, 11(1):1959-1972.

4. Zhou K^#*, Xue C ^#,Xu T^#, Shen P^#, Wei S, Wyres Kelly L., Lam Margaret M.C., Liu J, Lin H, Chen Y, Holt K, the BRICS Working Group, Xiao Y^*. A point mutation in recC associated with subclonal replacement of carbapenem-resistant Klebsiella pneumoniae ST11 in China.Nat Communs, 2023, 14: 2464.

5. Xu T^#, Zhang C^#, Ji Y, Song J, Liu Y, Guo Y, Zhou K^*. Identification of mcr-10 carried by self-transmissible plasmids and chromosome in Enterobacter roggenkampii strains isolated from hospital sewage water. Environ Pollut, 2021, 268(Pt B): 115706.