On the morning of March 11, 2025, at the invitation of Professor Xueji Zhang from the School of Biomedical Engineering, SZU Medicine School, Professor Chunying Chen, Academician of the Chinese Academy of Sciences and Researcher at the National Center for Nanoscience and Technology, delivered an academic lecture titled “Nano-Bio Interface and Nano Drug Regulation Strategies” as the distinguished guest of the 130th session of the “Medicine Forum.” The event was held at the School of Biomedical Engineering, Medical School. The forum attracted a large audience of faculty members and students from Lihu Campus.

添加图片描述  Nanotechnology is a transformative force in biomedicine, playing a criticial role in new drug development, precision medicine, and the diagnosis and treatment of diseases. Chunying Chen delivered an in-depth lecture on the chemical and biological properties of the nano-bio interface, the in vivo transport and metabolism of nanoparticles, and the targeted regulation strategies of smart nanodrugs. She also shared her team’s latest research advancements in areas such as nanomaterial behavior in vivo, nanodrug delivery systems, nano adjuvants, and immune regulation. Additionally, she discussed the broad significance of nanotechnology in addressing global public health challenges, overcoming barriers in new drug development, and advancing precision medicine.

During the lecture, Chunying Chen elaborated on the unique capabilities of nanoparticles to cross biological barriers, describing how her team employs stable isotope labeling techniques, single-cell X-ray imaging, and multi-omics data analysis to precisely track the metabolism and distribution of nanoparticles in vivo. She also highlighted recent progress in the clinical translation of nanodrugs for the treatment of cancer, infectious diseases, and genetic disorders, offering fresh perspectives on the innovative development of nanomedicine.

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During the Q&A session, faculty members and students actively engaged in discussions on topics such as the safety of nanodrugs, in vivo transport mechanisms, and the challenges of clinical translation. Chunying Chen shared her scientific insights and provided thoughtful, in-depth responses, encouraging young researchers to explore the intersection of nanotechnology and biomedicine and to contribute to the translation of fundamental research into clinical applications.

At the conclusion of the forum, Professor Xueji Zhang expressed sincere gratitude for Academician Chen’s enlightening presentation, noting how the session enhanced the academic community’s understanding of nano-bio interfaces and nanodrug regulation strategies, promoted interdisciplinary exchange between nanotechnology and biomedical science, and laid a strong foundation for future research collaborations.

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Professor Xueji Zhang presented Academician Chunying Chen with the "Shenyi Forum" Honorary Award 

in recognition of her contributions.

Brief introduction of the Speaker:

Chunying Chen is an Academician of the Chinese Academy of Sciences, Researcher at the National Center for Nanoscience and Technology, Doctoral Supervisor, and a New Cornerstone Investigator. She is a recipient of the National Science Fund for Distinguished Young Scholars and has served as the chief scientist for the National Key R&D Programs in "Nanotechnology" and "Frontiers in Nanotechnology". Professor Chen has led several major national and international research initiatives, including the National Natural Science Foundation’s Major Research Instrumentation Development Program, Key Research Projects of major programs, and multiple projects under the EU Sixth and Seventh Framework Programs.

Her numerous honours include the First Prize (2018) and Second Prize (2012) of the National Natural Science Award, the IUPAC Distinguished Women in Chemistry and Chemical Engineering Award, the National May 1st Female Role Model Award, the CAS Outstanding Scientific Achievement Award, and the Royal Society of Chemistry’s Environment Prize, among many other national and international accolades. She has been invited as an expert to major international bodies including ISO, WHO, and OECD, and currently serves as Executive Editor of ACS Nanoand on the editorial or advisory boards ofScience Bulletin and several other journals. She was named a “Leading Scientist” by Nature Nanotechnologyand featured in Nature’s People of Science interview series.

Professor Chen’s current research focuses on nano–protein corona analysis methods and its biochemical effects, the detection and mechanisms of nanomaterials' in vivo behaviour, and the development of nano adjuvants and delivery systems. She has published over 390 SCI papers in high-impact journals such asNature Nanotechnology, Nature Methods, Nature Communications, PNAS, JACS, and Angewandte Chemie. She holds 45 authorized Chinese invention patents, one international PCT patent (granted in the US, EU, and Japan), and has authored eight books in both Chinese and English, published by the Royal Society of Chemistry, Wiley (Germany), Science Press, and Metallurgical Industry Press.