Distinguished Professor

Dr. Liu earned his B.S. degree from Peking University in 1999, and Ph.D. degree at the University of Hong Kong in 2007. He completed postdoctoral training at the University of Hong Kong and was promoted to Research Assistant Professor in 2011. In 2014, Dr Liu joined Shenzhen University as a Distinguished Professor. During his career, Dr Liu has received awards including Li Ka Shing Prize.

Research Interests:

His research interests are centered on mechanisms and interventions of aging.

Research Projects:

1. Natural Science Foundation of China (NSFC; 91849208)      

Baohua Liu, PI                                                                       

2019 to 2022, RMB 1,500,000

2. Natural Science Foundation of China (NSFC; 81571374)        

Baohua Liu, PI

2016 to 2019,RMB 1,200,000

3.NSF of Guangdong Province Major Research Program (2015A030308007)    Baohua Liu, Co-Investigator

2016 to 2019, RMB 1,000,000

4. Shenzhen Basic Research Program (JCYJ20160226191451487)      

Baohua Liu, PI    

2016 to 2019, RMB 2,000,000

Selected Peer-reviewed Publications:

1. Xiaolong Tang, Guo Li, Fengting Su, Yanlin Cai, Lei Shi, Yuan Meng, Zuojun Liu, Jie Sun, Ming Wang, Minxian Qian, Zimei Wang, Xingzhi Xu, Yong-Xian Cheng, Wei-Guo Zhu, Baohua Liu*. HDAC8 cooperates with SMAD3/4 complex to suppress SIRT7 and promote cell survival and migration. Nucleic Acids Research 2020, accepted

2.Shimin Sun#, Weifeng Qin#, Xiaolong Tang#, Yuan Meng, Wenjing Hu, Shuju Zhang, Minxian Qian, Zuojun Liu, Xinyue Cao, Qiuxiang Pang, Bosheng Zhao, Zimei Wang, Zhongjun Zhou, Baohua Liu*. Vascular endothelium-targeted Sirt7 gene therapy rejuvenates aging tissues and extends lifespan in Hutchinson-Gilford progeria model. Science Advances 2020 accepted

3. Zuojun Liu#, Minxian Qian#, Xiaolong Tang, Wenjing Hu, Shimin Sun, Guo Li, Shuju Zhang, Fanbiao Meng, Xinyue Cao, Jie Sun, Cheng Xu, Bing Tan, Qiuxiang Pang, Bosheng Zhao, Zimei Wang, Youfei Guan, Xiongzhong Ruan, Baohua Liu*. SIRT7 couples light-driven body temperature cues to hepatic circadian phase coherence and gluconeogenesis. Nature Metabolism 2019, 1, pages1141–1156(2019)

4. Minxian Qian#, Zuojun Liu#, Linyuan Peng, Xiaolong Tang, Fanbiao Meng, Ying Ao, Mingyan Zhou, Ming Wang, Xinyue Cao, Baoming Qin, Zimei Wang, Zhongjun Zhou, Guangming Wang, Zhengliang Gao, Jun Xu, Baohua Liu*. Boosting ATM Activity alleviates ageing and extends lifespan in a mouse model of progeria. eLife 2018 May 2;7. pii: e34836. doi: 10.7554/eLife.34836.

5. Xiaolong Tang#, Lei Shi#, Ni Xie#, Zuojun Liu, Minxian Qian, Fanbiao Meng, Qingyang Xu, Minyan Zhou, Xinyue Cao, Wei-Guo Zhu, Baohua Liu*. SIRT7 Antagonizes TGF-β Signaling and Inhibits Breast Cancer Metastasis. Nature Communications 2017 Aug 22;8(1):318. doi: 10.1038/s41467-017-00396-9