科研项目
国家自然科学基金：
1，抗原/VIP融合蛋白疫苗调节肠粘膜免疫耐受、抑制食物过敏反应的机理研究（31570932）
2，表达TSP1的耐受型B细胞抑制食物过敏反应的作用机理研究（81373176）
3，抗IgE-ε链单克隆抗体对实验性过敏反应的抑制作用研究（92030310）
加拿大国立卫生研究院基金：
1，Title: Role of A20 in regulation of intestinal immunity. $664,000. (320068)
2，Title: Role of gut bacterial derived peptidoglycan in the induction of immune inflammation in the intestine. $450,000.00. (220058)
3，Title: Impact on the biology of mucosal tolerance in exposure to haptenated antigens $625,000.00.(371268)
4，Title: Role of dendritic cell in oral tolerance and food allergy. $600,715.00. (191063)
5，Title: Role of low IgE receptor in regulating intestinal epithelial barrier function. $300,000.00. (177843)
代表性成果
Zheng PY, Geng XR, Hong JY, Yang G, Liu JQ, Mo LH, Feng Y, Zhang YY, Liu T, Ran P, Liu ZG*, Yang PC*. Regulating Bcl2L12 expression in mast cells inhibits food allergy. Theranostics. 2019; 9 (17): 4982-4992.
Liu XY, Wu YJ, Song LJ, Zeng XH, Wang S, Liu JQ, Mo LH, Geng XR, Yang LT, Zhang XW*, Liu ZG*, Yang PC*. 3-methyl-4-nitrophenol regulates dendritic cell activities to facilitate the development of nasal allergy. J Allergy Clin Immunol 2019;143(4):1614-1616.
Yang G, Geng XR, Song JP, Wu YY, Yan H, Zhan Z, Yang L, He W, Liu ZQ, Qiu S, Liu Z, Yang PC*. Insulin-like growth factor-2 enhances regulatory T cell functions and suppresses food allergy in an experimental model. J Allergy Clin Immunol 2014; 133(6): 1702-1708.
Wu W, Sun M, Zhang HP, Chen T, Wu R, Liu C, Yang G, Geng XR, Feng BS, Liu ZG, Liu Z*, Yang PC*. Prolactin mediates psychological stress-induced dysfunction of regulatory T cells to facilitate intestinal inflammation. Gut. 2014. 63 (12): 1883-92.
He SH, Chen X, Song CH, Liu ZQ, Zhou LF, Ma WJ, Zhao LD, Li TL, Tang SG, Xing Z, Yang PC . A novel interferon lambda-mediated pathway in establishment of oral tolerance and inhibition of antigen-specific Th2 polarized gut inflammation. Gastroenterology 2011; 141:249-258.
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