1.国家自然科学基金面上项目：82070806，探讨cAMP-PKA-ChREBP调控的COX6A2在胃旁路手术减少2型糖尿病胰岛β细胞凋亡中的作用及机制。
2.国家自然科学青年基金：81400801,蛋白激酶ERK1/2介导GLP-1改善胰岛β细胞功能障碍作用研究。
2.深圳市基础研究项目基金：JCYJ20160307155501522, GLP-1R介导胃旁路手术改善糖尿病大鼠胰岛素分泌作用研究。
3.深圳市基础研究项目基金：JCYJ20130326112700890，用光学成像方法研究微管结合蛋白调控胰岛素分泌的机制。
1.Kong X, Feng L, Yan D, Li B, Yang Y, Ma X. FXR-mediated epigenetic regulation of GLP-1R expression contributes to enhanced incretin effect in diabetes after RYGB.J Cell Mol Med. 2021 Feb 21. doi: 10.1111/jcmm.16339.
2.Kong XC, Tu YF, Li BF, Zhang LM, Feng LX, Wang LX, Zhang L, Zhou HR, Hua XX, Ma XS. Roux-en-Y gastric bypass enhances insulin secretion in type 2 diabetes via FXR-mediated TRPA1 expression. Molecular Metabolism. 2019, 29:1-11.
3.Xing B, Ma J, Jiang Z, Feng Z, Ling S, Szigety K, Su W, Zhang L, Jia R, Sun Y, Zhang L, Kong X, Ma X, Hua X. GLP-1 signaling suppresses menin's transcriptional block by phosphorylation in β cells. J Cell Biol. 2019, 218(3):855-870.
4.Matkar S, Sharma P, Gao S, Gurung B, Katona BW, Liao J, Muhammad AB, Kong XC, Wang L, Jin G, Dang CV, Hua X. An Epigenetic Pathway Regulates Sensitivity of Breast Cancer Cells to HER2 Inhibition via FOXO/c-Myc Axis. Cancer Cell. 2015, 28(4):472-85.
5.Kong X, Yan D, Sun J, Wu X, Mulder H, Hua X, Ma X. Glucagon-Like Peptide 1 Stimulates Insulin Secretion via Inhibiting RhoA/ROCK Signaling and Disassembling Glucotoxicity-Induced Stress Fibers. Endocrinology. 2014, 155(12):4676-85.
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