代表性成果

1.Xiaopeng Lu, Min Xu, Qian Zhu, Jun Zhang, Ge Liu, Yantao Bao, Luo Gu, Yuan Tian, He Wen, and Wei-Guo Zhu^*. RNF8-ubiquitinated KMT5A is required for RNF168-induced H2A ubiquitination in response to DNA damage. FASEB J. 2021 Apr;35(4):e21326.

2.Jun Zhang ^#, Xiaopeng Lu ^#, Sara MoghaddamKohi, Lei Shi, Xingzhi Xu, Wei-Guo Zhu. Histone lysine modifying enzymes and their critical roles in DNA double-strand break repair. DNA Repair (Amst). 2021 Aug 12;107:103206.

3.Xiaopeng Lu^#, Ming Tang^#, Qian Zhu, Qiaoyan Yang, Zhiming Li, Yantao Bao, Ge Liu, Tianyun Hou, Yafei Lv, Ying Zhao, Haiying Wang, Yang Yang, Zhongyi Cheng, He Wen, Baohua Liu, Xingzhi Xu, Luo Gu, Wei-Guo Zhu^*. GLP-catalyzed H4K16me1 promotes 53BP1 recruitment to permit DNA damage repair and cell survival. Nucleic Acids Res. 2019 Dec 2; 47(21):10977-10993.

4.Ming Tang^#, Xiaopeng Lu^#, Chaohua Zhang, Changzheng Du, Linlin Cao, Tianyun Hou, Zhiming Li, Bo Tu, Ziyang Cao, Yinglu Li, Yongcan Chen, Lu Jiang, Hui Wang, Lina Wang, Baohua Liu, Xingzhi Xu, Jianyuan Luo, Jiadong Wang, Jin Gu, Haiying Wang, Wei-Guo Zhu*. Downregulation of SIRT7 by 5-fluorouracil induces radiosensitivity in human colorectal cancer. Theranostics. 2017 Mar 22;7(5):1346-1359.

5.Qian Zhu, Qiaoyan Yang, Xiaopeng Lu, Hui Wang, Lili Tong, Zheng Li, Ge Liu, Yantao Bao, Xingzhi Xu, Luo Gu, Jian Yuan, Xiangyu Liu, Wei-Guo Zhu. SETD2-mediated H3K14 trimethylation promotes ATR activation and stalled replication fork restart in response to DNA replication stress.PNAS. 2021 Jun 8;118(23):e2011278118.