1. Man Zhao,† Wenjing Ma,† Jinyi Liang,† Yubao Xie, Tianzi Wei, Ming Zhang, Jiajie Qin, Lingyin Lao, Ruilin Tian, Haiqiang Wu, Jin Cheng, Min Li,* Yuyang Liu,* LiangHong* and Guofeng Li*, Design, Synthesis, and Activity Evaluation of BRD4 PROTAC Based on Alkenyl Oxindole-DCAF11 Pair. J. Med. Chem. 2024, 67, 19428-19447.
2. Yuyang Liu,† Guofeng Li,† Wen Ma, Guangjun Bao, Yiping Li, Zeyuan He, Zhaoqing Xu*, Rui Wang* and Wangsheng Sun*, Late-stage peptide modification and macrocyclization enabled by tertiary amine catalyzed tryptophan allylation, Chem. Sci. 2024, 15, 11099-11107.
3. Ying Wang,† Tianzi Wei,† Man Zhao,† Aima Huang, Fan Sun, Lu Chen, Risheng Lin, Yubao Xie, Ming Zhang, Shiyu Xu, Zhihui Sun, Liang Hong*, Rui Wang*, Ruilin Tian*, Guofeng Li*, Discovery of alkenyl oxindole as a novel PROTAC moiety for targeted protein degradation via CRL4DCAF11 recruitment. PLOS Biol. 2024, 22, e3002550.
4. Shiyu Xu, Zhihui Sun, Pengyutian Liu, Yuanlin Wei, Fan Sun, Man Zhao, Ying Wang, Ming Zhang*, Guofeng Li* and Hong Liang*, DBU-catalyzed substitution-controlled synthesis of oxa[3.3.1] bridged ring and naphthylamine derivatives, Org. Chem. Front. 2024, 11, 2845-2850.
5. Ying Wang, Aima Huang, Lu Chen, Fan Sun, Man Zhao, Ming Zhang, Yubao Xie, Shiyu Xu, Min Li*, Liang Hong*, Guofeng Li* and Rui Wang*, Design and synthesis of dual BRD4/Src inhibitors for treatment of triple-negative breast cancer, Eur. J. Med. Chem. 2024, 116009.
6. Man Zhao,† Weizhen Fan,† Ying Wang,† Pengfei Qiang, Zhihua Zheng, Hao Shan, Ming Zhang, Pengyutian Liu, Yao Wang, Guofeng Li*, Min Li* and Liang Hong*, M335, a novel small-molecule STING agonist activates the immune response and exerts antitumor effects, Eur. J. Med. Chem. 2024, 264, 116018.
7. Xiaobin You, Ying Yao, Pengyutian Liu, Lu Chen, Yubao Xie, Guofeng Li*, and Liang Hong*, Synthesis of Isoquinuclidines via Dearomative Diels–Alder Reaction of Cyclic Amidines with Indoles, J. Org.Chem. 2024, 89, 3635−3643.
8. Shiyu Xu,† Aima Huang,† Yang Yang, Ying Wang, Ming Zhang, Zhihui Sun, Man Zhao, Yuanlin Wei, Guofeng Li* and Liang Hong*, Organocatalytic Enantioselective Construction of Spiroketal Lactones Bearing Axial and Central Chirality via an Asymmetric Domino Reaction, Org. Lett. 2022, 24, 2978-2982.
9. Ying Wang, Yang Yang, Shiyu Xu, Aima Huang, Lu Chen, Yubao Xie, Pengyutian Liu, Liang Hong and Guofeng Li*, Organocatalytic Enantioselective Construction of Axially Chiral (1H)-isochromen-1-imines, Org. Biomol. Chem. 2022, 20, 3277-3282.
10. Guangjun Bao,† Peng Wang,† Guofeng Li,† Changjun Yu, Yiping Li, Yuyang Liu, Zeyuan He, Jing Rao, Junqiu Xie, Wangsheng Sun* and Rui Wang*, Exploration and application of 1,3-Dipolar cycloaddition between dehydroalanines and C,N-Cyclic azomethine imines: A route to late-stage peptide modification, Angew. Chem. Int. Ed. 2021, 60, 5331-5338.
11. Guofeng Li,† Man Zhao,† Junqiu Xie,† Ying Yao, Lingyun Mou, Xiaowei Zhang, Xiaomin Guo, Wangsheng Sun, Zheng Wang, Jiecheng Xu, Jianzhong Xue, Tao Hu, Ming Zhang, Min Li* and Liang Hong*, Efficient synthesis of cyclic amidine-based fluorophores via 6π-electrocyclic ring closure, Chem. Sci. 2020, 11, 3586-3591.
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