近5年主持的科研项目
1.广东省自然科学基金面上项目, 2023A1515012475, 2023.1-2025.12, 在研,主持。
2.深圳市科创委面上项目,JCYJ20210324093810026,2021.10-2024.10,在研,主持。
3.深圳市科创委面上项目,JCYJ20190808164201654,2020.05-2023.04,结题,主持。
4.广东省医学基金面上项目,A2020272,2020.07-2022.06,结题,主持。
5.深圳市高层次人才启动项目,827/00035,2019.01-2021.12,结题,主持。
6.深圳市桦健量子生物科技有限公司,企业委托,2019.05-2020.04,结题,主持。
7.国家自然科学基金地区基金项目,81560676,2016.01-2019.12,结题,主持。
近5年代表性学术论文
1.Zhai L, Xiao H (共同一作), Lin C, Wong HLX, Lam YY, Gong M, Wu G, Ning Z, Huang C, Zhang Y, Yang C, Luo J, Zhang L, Zhao L, Zhang C, Lau JY, Lu A, Lau LT, Jia W, Zhao L, Bian ZX. Gut microbiota-derived tryptamine and phenethylamine impair insulin sensitivity in metabolic syndrome and irritable bowel syndrome. Nat Commun. 2023, 14(1):4986.
2. Huan, Q, Peng, J, Chang, Y, Zhang, Q, Xing, T, Jiang, D, Chen, W, Shen, X, Bian, Z, Xiao, H (通讯作者). Activation of P2Y1R impedes intestinal mucosa repair during colitis. Int. J. Biol. Sci. 2023, 19 (14), 4360-4375.
3.Peng J, Deng H, Du B, Wu P, Duan L, Zhu R, Ning Z, Feng J, Xiao H (通讯作者). Saffron petal, an edible byproduct of saffron, alleviates dextran sulfate sodium-induced colitis by inhibiting macrophage activation and regulating gut microbiota. J Agric Food Chem. 2023, 71(28):10616-10628.
4.Zhai LX, Peng J, Zhuang M, Chang YY, Cheng KW, Ning ZW, Huang T, Lin CY, Wong HL Xavier, Lam YY, Tan HY, Xiao HT (共同通讯作者), Bian ZX. Therapeutic effects and mechanisms of Zhen-Wu-Bu-Qi Decoction on dextran sulfate sodium-induced chronic colitis in mice assessed by multi-omics approaches. Phytomedicine. 2022, 99: 154001.
5.Chang YY, Huan QC, Peng J, Bi WC, Zhai LX, Chen Y, Lamb JR, Shen XC, Bian ZX,Wu HQ, Cheng YX, Xiao HT (通讯作者). P2Y1R ligation suppresses Th17 cell differentiation and alleviates colonic inflammation in an AMPK-dependent manner. Front Immunol.2022, 13: 820524.
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